Abstract: Leaching by sulfuric acid, the low-grade uranium ore extraction and purification using D2EHPA; The results show that①In the optimized conditions, the rate of leaching reachs 83.75%. ②the extraction effect is good using D2EHPA and the rate of extraction reachs 99.99%. ③In the deposition of weight uranium by ammonia acid the precipitation rate can reachs 99.91%. This process is simplify, and the total recovery rate is high (up to 83.23%). with hespect to the extraction process under the conventional conditions. it is easier to controling the producting process; and the advantages is obvious.