Abstract: This paper studies the effects of PH value, carbon chain length and structure of xanthate on the flotation behaviors of cerusite.It is necessary to sulfide cerusite using xanthate as the collector, and the best range of PH for sulfuration is 8~10.The longer the carbon chain, the better the collecting effect.And the flotation effect of the isomer xanthate is better than that of the normal structure.The cerusite can be collected by xanthate without sulfuration, however the flotation indexes are not good.