Abstract: In order to manage a full resource recovery of the laterite-nickel ore and achieve the purpose of clean production, the paper introduces the methods of leaching the Laterite-nickel ore with high acid, pre-neutralizing the lixivium with noumeite and collecting the filter liquor, removing iron from the liquor by using magnesite and collecting the nonferrous filtrate, applying magnesite to the filtrate to make nickel precipitate, and concentrating the nickel-free filtrate to obtain crystallized high-purity magnesium sulfate, which can produce downstream products of high-purity magnesium. In this way the iron residue can be used in iron-making, and the residue of leaching and pre-neutralization could produce silica white.