Abstract: The rapid development of the chemical industry leads to a large amount of high salt organic wastewater, and it is also increasing year by year. The difficulty and cost involved in dealing with high salt organic wastewater are very high due to its properties of high salinity and refractory. In this paper, we reviewed the advantages and disadvantages of various methods for its treatment and focused on the research progress and application of various processes. Comprehensive analysis suggests that its research should focus on developing new materials and reagents, exploring efficient and energy-saving physicochemical-biochemical combination process, improving the efficiency in its treatment and reducing treatment costs.