Abstract: In recent years, the frequent geological disasters in the slopes of mining areas, which seriously threaten people's lives and property, have become the focus of the society. Therefore, it is an urgent problem for current slope monitoring engineering to find an automatic deformation monitoring technology that can acquire monitoring data in real time and dynamically, along with quick and accurate analysis and prediction for the deformation mechanism of slope. Based on measuring robots, online analysis and prediction technology of open pit slope automatically corrected the three-dimensional coordinate values of the monitoring points, analyzed the deformation characteristics of the slope from time and space, and reasonably predicted the future development trend of the slope in the mining area by controlling the measuring robot to implement remote, long-term and accurate unmanned observation of the slope. Taking a mine monitoring test in Guangdong as an example, the results showed that, from the perspective of time continuity, the slope changed in the horizontal direction with the eastward shifting. And the mining area, which was sinking in the vertical direction, was predicted to collapse. The danger of the space was that the deformation was concentrated in the western part of the deformation zone and the scatter zone in the middle. The displacement deformation near the mining area was greater than that of away from the mining area, indicating the great impact of mining on the slope deformation. After field measurement, it was proved that the technology was suitable for automatic monitoring of remote, unmanned, long-term and all-weather in mine slope engineering.