Abstract: According to the weld profile and depth width ratio of the electron beam welding, the combined heat source was selected as the heat source model. Parameters of materials thermodynamic with temperature variation were estimated by linear interpolation and another method, the temperature field of Ti-based amorphous alloy by electron beam welding was simulated. The simulation results and the actual weld achieved good match, the accuracy of heat source model was tested. Temperature field and thermal cycle curve of Ti-based amorphous alloy by electron beam welding under variable parameter were obtained. To obtain the residual stress distribution curve, the stress field on the basis of temperature field was simulated. Experiment show that the whole welding part has no crystallization phase, the feasibility of the welding process is verified.