Abstract: Using titanium mesh as the diffusion layer substrate, chloroiridic acid as the precursor, oxygen evolution anode of IrO₂/Ti was prepared by the thermal decomposition method, and then the membrane electrode assembly was prepared via the hot-press method. The effects of performance and life caused by different layer of titanium mesh oxygen evolution anode was investigated by scanning electron microscopy, cyclic voltammogram, alternating current impedance, cell performance curve test and anode accelerated life test. The results show that the integral charge increased from 84.27 mC/cm² to 153.12 mC/cm² and the electrochemical reaction impedance was decreased from 7.38 ohm·cm² to 3.03 ohm·cm² both in the single layer Ti mesh and double layer Ti mesh with the improved cell performance. Accelerated life tests show that it has a significant boost in stability and life from single to double layer. The life of the titanium mesh oxygen evolution anode increased from 30 h to 53 h.