Abstract: Qianjiaping vanadium ore is the large scale underground mines adopting the medium-length hole caving method to stope. Because of the confined workspace, high operating frequency and large single charge during the blasting operation, the stability of adjacent ore -drawing roadway can be affected by blasting vibration easily. In order to study the impact of ore -drawing roadway on medium -length hole blasting and ensure the stability of ore-drawing roadway, the fluid-structure interaction of ANSYS/LS-DYNA was used to analyze the stoping roadway's vibration intensity on one blasting operation. No obvious deviation is found by comparing the results of numerical calculation with that of the field measurement, which indicates that the application of ANSYS/LS -DYNA to the prediction of the vibration intensity of medium -length hole blasting has guiding significance.