Abstract: This paper studies the flowsheet of "pre-desulfurization floatation-centrifuge preenrichment gravity separation-wolframite slime floatation" based on the features of a low grade wolframite slime. The test results show that after the application of the flowsheet of twice roughing sulfur removal, roughing-cleaning centrifuge preenrichment by gravity separation, then roughing three times and cleaning twice scavenging separating wolframite by flotation, the tungsten concentrate with the grade of 33.80 % and the recovery of 61.08 % could be obtained. The tungsten minerals are well recoverd from wolframite slime with the recovery rate of 64.27 %. The flowsheet is cost -effective and environment -friendly for reduced beneficiation reagents dosages by adopting roughing enrichment measures of pre-desulfurization and centrifugal separator .